Leveraging Genomic Factors to Improve Benefit–Risk
نویسندگان
چکیده
Genomic and other molecular factors frequently impact the efficacy, safety, and pharmacokinetic (PK) profiles of therapeutic products. Recent advances in our understanding of how these factors contribute to interindividual variability in drug response has led to the use of genomic strategies to improve clinical trial design in the drug development setting, and also to guide patient care in the clinical setting.1,2
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